Amino acids, often referred to as the building blocks of proteins, are compounds that play many critical roles in your body. They're needed for vital processes like the building of proteins and synthesis of hormones and neurotransmitters. Some may also be taken in supplement form for a natural way to boost athletic performance or improve mood. Out of 20 amino acids only 9 are essentials which are histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine as they can’t be made human body.

Indications:

⇒ Useful in muscle tissue recovery and for the muscle metabolism, while increasing exercise endurance (Very useful to athletes & body-builders)
⇒ Increases production of growth hormones, and helps burn visceral fat
⇒ Promotes the healing of bones, skin, and muscle tissue after traumatic injury, and is often recommended for those recovering from surgery
⇒ Helps regulate mood and stimulates the nervous system
⇒ Boosts energy & supports immune system
⇒ Helps regulate appetite, pain sensitivity, and the body's response to stress
⇒ Helps you feel happier, less hungry and more alert
⇒ Necessary for normal growth and development
⇒ Assists in formation of collagen and elastin in the skin

About Composition:

Isoleucine, Leucine & Valine are three branched chain amino acids.Isoleucine is intermediate for its ability to induce muscle protein synthesis but is able to significantly increase glucose uptake and the usage of glucose during exercise. Branched-chain amino acids stimulate the building of protein in muscle and possibly reduce muscle breakdown. Branched-chain amino acids seem to prevent faulty message transmission in the brain cells of people with advanced liver disease, mania, tardive dyskinesia, and anorexia.

Methionine is sulfur containing essential amino acid and belongs to a group of compounds called lipotropics - the others in this group include choline, inositol, and betaine. It is important in the process of methylation where methyl is added to compounds as well as being a precursor to the amino acids cystine and cysteine. The amino acid methionine is also a great antioxidant as the sulfur it supplies inactivates free radicals. It may also be used to treat depression, arthritis pain as well as chronic liver disease - although these claims are still under investigation. Some studies have also indicated that methionine might improve memory recall.

Tyrosine has a special role by virtue of the phenol functionality. It occurs in proteins that are part of signal transduction processes and functions as a receiver of phosphate groups that are transferred by way of protein kinases. Phosphorylation of the hydroxyl group can change the activity of the target protein, or may form part of a signaling cascade via SH2 domain binding. A tyrosine residue also plays an important role in photosynthesis. In chloroplasts (photosystem II), it acts as an electron donor in the reduction of oxidized chlorophyll. In this process, it loses the hydrogen atom of its phenolic OH-group. This radical is subsequently reduced in the photosystem II by the four core manganese clusters. In dopaminergic cells in the brain, tyrosine is converted to L-DOPA by the enzyme tyrosine hydroxylase (TH). TH is the rate-limiting enzyme involved in the synthesis of the neurotransmitter dopamine. Dopamine can then be converted into other catecholamines, such as norepinephrine (noradrenaline) and epinephrine (adrenaline).

Phenylalanine is an essential a-amino acid. The L-isomer is used to biochemically form proteins, coded for by DNA. Phenylalanine is a precursor for tyrosine, the monoamine neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline), and the skin pigment melanin. It is encoded by the codons UUU and UUC. Phenylalanine is found naturally in the breast milk of mammals. It is used in the manufacture of food and drink products and sold as a nutritional supplement for its reputed analgesic and antidepressant effects. It is a direct precursor to the neuromodulator phenethylamine, a commonly used dietary supplement. As an essential amino acid, phenylalanine is not synthesized de novo in humans and other animals, who must ingest phenylalanine or phenylalanine-containing proteins.

Lysine is an essential amino acid and is a basic building block of all protein. It is required for growth and bone development in children, assists in calcium absorption and maintaining the correct nitrogen balance in the body and maintaining lean body mass. Furthermore it is needed to produce antibodies, hormones, enzymes, collagen formation as well as repair of tissue. Since it helps with the building of muscle protein, it is useful for patients recovering from injuries and recovery after operations, and there might be used in lysine to help maintain healthy blood vessels.

Threonine is an amino acid that is used in the biosynthesis of proteins. It is essential in humans, meaning the body cannot synthesize it: it must be obtained from the diet. Threonine is an essential amino acid that helps to maintain the proper protein balance in the body. It is important for the formation of collagen, elastin, and tooth enamel, and aids liver and lipotropic function when combined with aspartic acid and methionine. Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in controlling fat build-up in the liver. May help combat mental illness and may be very useful in indigestion and intestinal malfunctions. Also, threonine prevents excessive liver fat. Nutrients are more readily absorbed when threonine is present.

Histidine is a a-amino acid that is used in the biosynthesis of proteins. It may have some immunomodulatory as well as antioxidant activity. L-histidine may be indicated for use in some with rheumatoid arthritis. It is not indicated for treatment of anemia or uremia or for lowering serum cholesterol. Is found abundantly in hemoglobin; has been used in the treatment of rheumatoid arthritis, allergic diseases, ulcers and anemia. A deficiency can cause poor hearing. L-histidine is the obligate precursor of histamine, which is produced via the decarboxylation of the amino acid. In experimental animals, tissue histamine levels increase as the amount of dietary L-histidine increases. It is likely that this would be the case in humans as well. Histamine is known to possess immunomodulatory and antioxidant activity. Suppressor T cells have H2 receptors, and histamine activates them. Promotion of suppressor T cell activity could be beneficial in rheumatoid arthritis. Further, histamine has been shown to down-regulate the production of reactive oxygen species in phagocytic cells, such as monocytes, by binding to the H2 receptors on these cells. Decreased reactive oxygen species production by phagocytes could play antioxidant, anti-inflammatory and immunomodulatory roles in such diseases as rheumatoid arthritis.

Tryptophan is an essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals. Tryptophan is critical for the production of the body's proteins, enzymes and muscle tissue. It is also essential for the production of niacin, the synthesis of the neurotransmitter serotonin and melatonin. Tryptophan supplements can be used as natural relaxants to help relieve insomnia. Tryptophan can also reduce anxiety and depression and has been shown to reduce the intensity of migraine headaches. Other promising indications include the relief of chronic pain, reduction of impulsivity or mania and the treatment of obsessive or compulsive disorders. Tryptophan also appears to help the immune system and can reduce the risk of cardiac spasms. Tryptophan deficiencies may lead to coronary artery spasms. Tryptophan is used as an essential nutrient in infant formulas and intravenous feeding. Tryptophan is marketed as a prescription drug (Tryptan) for those who do not seem to respond well to conventional antidepressants. It may also be used to treat those afflicted with seasonal affective disorder (a winter-onset depression). Tryptopan serves as the precursor for the synthesis of serotonin (5-hydroxytryptamine, 5-HT) and melatonin (N-acetyl-5-methoxytryptamine).

Side Effects:

The product is possible safe for most adults. There is no disadvantage associated with the product if taken under the recommended usage however nausea, vomiting and headache can occur at normal doses.

Contraindication:

⇒ Avoid alcohol consumption
⇒ Do not take antacid along with the supplements
⇒ Renal or hepatic impairment

Warning & Precaution:

⇒ Do not exceed the recommended dose
⇒ Keep out of reach of children
⇒ The combination should only be used in pregnancy and lactation if benefits outweigh the risks.

Storage:

⇒ Store at room temperature.
⇒ Protect from light.
⇒ Store in a dry place